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Effects of selection on residual feed intake and diet on gene expression in pig perirenal adipose tissue

ABSTRACT: Transcriptional profiling in peritoneal adipose tissue of 48 pigs (132 days of age) originated from two lines divergently selected for residual feed intake (RFI) : low-RFI pigs (RFIneg), high-RFI pigs (RFIpl). Both lines were offered isocaloric and isoproteic diets with contrasted energy source and nutrients: low fat, low fiber (LF) diet or a high fat, high fiber (HF)diet during 10 weeks. Effects of RFI selection, diet and interaction between diet and line were investigated. Four experimental groups: low-RFI pigs fed high fat, high fiber diet (HF_RFIneg), high-RFI pigs fed high fat, high fiber diet(HF_RFIpl), low-RFI pigs fed low fat, low fiber diet (LF_RFIneg) and high-RFI pigs fed low fat, low fiber diet(LF_RFIpl). 12 pigs per condition. One replicate per array.

ORGANISM(S): Sus scrofa

SUBMITTER: Annie Vincent

PROVIDER: E-GEOD-70837 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Molecular alterations induced by a high-fat high-fiber diet in porcine adipose tissues: variations according to the anatomical fat location.

Gondret Florence F Vincent Annie A Houée-Bigot Magalie M Siegel Anne A Lagarrigue Sandrine S Louveau Isabelle I Causeur David D

BMC genomics 20160218

<h4>Background</h4>Changing the energy and nutrient source for growing animals may be an effective way of limiting adipose tissue expansion, a response which may depend on the genetic background of the animals. This study aims to describe the transcriptional modulations present in the adipose tissues of two pig lines divergently selected for residual feed intake which were either fed a high-fat high-fiber (HF) diet or an isocaloric low-fat high-starch diet (LF).<h4>Results</h4>Transcriptomic ana ...[more]

PMID: 26892011

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