RNA-seq performed on sarcomas to identify various alterations
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Tom Lesluyes
PROVIDER: E-GEOD-71119 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
RNA sequencing validation of the Complexity INdex in SARComas prognostic signature.
Lesluyes Tom T Pérot Gaëlle G Largeau Marine Roxane MR Brulard Céline C Lagarde Pauline P Dapremont Valérie V Lucchesi Carlo C Neuville Agnès A Terrier Philippe P Vince-Ranchère Dominique D Mendez-Lago Maria M Gut Marta M Gut Ivo I Coindre Jean-Michel JM Chibon Frédéric F
European journal of cancer (Oxford, England : 1990) 20160223
<h4>Background</h4>Prognosis of metastatic outcome in soft tissue sarcomas is an important clinical challenge since these tumours can be very aggressive (up to 50% of recurring events). A gene expression signature, Complexity INdex in SARComas (CINSARC), has been identified as a better prognostic factor compared to the current international grading system defined by the Fédération Nationale des Centres de Lutte Contre le Cancer. Since CINSARC has been established on frozen tumours analysed by mi ...[more]
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