Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Adam Gower
PROVIDER: E-GEOD-72157 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Estrella Nelsa L NL Clark Amanda L AL Desjardins Cody A CA Nocco Sarah E SE Naya Francisco J FJ
The Journal of biological chemistry 20150820 40
The cardiomyocyte cell cycle is a poorly understood process. Mammalian cardiomyocytes permanently withdraw from the cell cycle shortly after birth but can re-enter the cell cycle and proliferate when subjected to injury within a brief temporal window in the neonatal period. Thus, investigating the mechanisms of cell cycle regulation in neonatal cardiomyocytes may provide critical insight into the molecular events that prevent adult myocytes from proliferating in response to injury or stress. MEF ...[more]