Genome-wide microRNA-expression analysis after p53 activation in hepatocellular carcinoma
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ABSTRACT: In order to characterize the differentially expressed miRNAs after the p53 activation , small RNA-seq were used after the overexpression of p53 in HepG2 cells. Four samples of HepG2 cells were subjected to small RNA-seq in two biological replicates.The HepG2 cells were treated with 1µg/ml doxorubicin for 24 hours to induce the expression of p53. The experimental group(dox-treated HepG2ï¼HepG2_24h_rep1 and HepG2_24h_rep2) and control group(untreated HepG2: HepG2_0h_rep1 and HepG2_0h_rep2) were subjected to small RNA-seq to identify the p53-regulated miRNAs.
ORGANISM(S): Homo sapiens
SUBMITTER: Ding ruofan
PROVIDER: E-GEOD-74588 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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