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Time Course of Adults Vaccinated with Influenza TIV Vaccine during 2010/11 Flu Season (FluCenter cohort)

ABSTRACT: Systems approaches have been used to describe molecular signatures driving immunity to influenza vaccination in humans. Whether such signatures are similar across multiple seasons, and in diverse populations is unknown. We applied systems approaches to study immune responses in young and, elderly subjects vaccinated with the seasonal influenza vaccine across 5 consecutive seasons. During the 2010 Influenza season, healthy adults were vaccinated with TIV, and blood samples isolated at days 0, 3, 7 post-vaccination. Microarrays were performed using total RNA extracted from the peripheral blood mononuclear cells of vaccinees.

ORGANISM(S): Homo sapiens

SUBMITTER: Helder Nakaya

PROVIDER: E-GEOD-74815 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Time Course of Adults Vaccinated with Influenza TIV Vaccine during 2010/11 Flu Season (HIPC cohort)

Project description:Systems approaches have been used to describe molecular signatures driving immunity to influenza vaccination in humans. Whether such signatures are similar across multiple seasons, and in diverse populations is unknown. We applied systems approaches to study immune responses in young and, elderly subjects vaccinated with the seasonal influenza vaccine across 5 consecutive seasons. During the 2010 Influenza season, healthy adults were vaccinated with TIV, and blood samples isolated at days 0, 1, 3, 7, 14 post-vaccination. Microarrays were performed using total RNA extracted from the peripheral blood mononuclear cells of vaccinees.

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Time Course of Adults Vaccinated with Influenza TIV Vaccine during 2010/11 Flu Season (FluCenter cohort)

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Time Course of Adults Vaccinated with Influenza TIV Vaccine during 2010/11 Flu Season (HIPC cohort)

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Time Course of Adults Vaccinated with Influenza TIV Vaccine during 2011/12 Flu Season

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Time Course of Adults Vaccinated with Influenza TIV Vaccine during 2009/10 Flu Season

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Time Course of Young Adults Vaccinated with Influenza TIV Vaccine during 2008/09 Flu Season

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