Unknown,Transcriptomics,Genomics,Proteomics

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Expression data from CD8alpha positive dendritic cells


ABSTRACT: We screened a number of interferon inducible genes that may be involved in impeding HBV replication and found an anti-HBV activity in ISG20. ISG20 is an IFN-inducible 3â??- to 5â??-exonuclease, that degrades DNA and RNA and reduces antigen production in hepatocyte-derived cells A range of candidate genes whose expression was dependent on type I IFN stimulation were identified by gene arrays Total RNA from CD8α+ DCs was extracted from mouse spleens 8h after polyI:C (50 μg) stimulation by RNeasyTM kit. Total RNA (10 μg) from each sample was used to prepare cRNA. Gene expression was analyzed with GeneChipTM

ORGANISM(S): Mus musculus

SUBMITTER: Hiroyuki Oshiumi 

PROVIDER: E-GEOD-75690 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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