Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

The immunomodulatory effects of IL-4 on monocyte-derived macrophages


ABSTRACT: To explore the effects of IL-4 on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. We then stimulated these macrophages with or without IL-4 (20 ng/ml) for 6 hours and examined gene expression using a cDNA microarray. IL-4 stimulated gene expression on monocyte-derived macrophages was measured at 6 hours after exposure to doses of 20 ng/ml IL-4.

ORGANISM(S): Homo sapiens

SUBMITTER: Masayuki Asano 

PROVIDER: E-GEOD-75829 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2015-08-24 | E-GEOD-72292 | biostudies-arrayexpress
2015-07-14 | E-GEOD-70821 | biostudies-arrayexpress
2016-08-10 | E-GEOD-85346 | biostudies-arrayexpress
2014-12-13 | E-GEOD-53295 | biostudies-arrayexpress
2014-08-01 | E-GEOD-59948 | biostudies-arrayexpress
2016-03-08 | E-GEOD-77719 | biostudies-arrayexpress
2013-03-15 | E-GEOD-36537 | biostudies-arrayexpress
2016-08-25 | E-GEOD-86020 | biostudies-arrayexpress
2012-12-07 | E-GEOD-27658 | biostudies-arrayexpress
2011-01-10 | GSE19941 | GEO