Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

55 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Different gene expression signatures in children and adults with celiac disease

ABSTRACT: We collected 19 duodenal biopsies of children and adults with celiac disease and compared the expression of 38 selected genes between each other and with the observed in 13 non-celiac disease controls matched by age. qPCR gene expression profiling. Intestinal samples from children and adults with active celiac disease patients and controls were analysed.

ORGANISM(S): Homo sapiens

SUBMITTER: ConcepciÃ³n NÃºÃ±ez

PROVIDER: E-GEOD-76168 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Different gene expression signatures in children and adults with celiac disease

Project description:We collected 19 duodenal biopsies of children and adults with celiac disease and compared the expression of 38 selected genes between each other and with the observed in 13 non-celiac disease controls matched by age.

2015-12-19 | GSE76168 | GEO

miRNA profiling of celiac disease

Project description:microRNAs were profiled in healthy controls, classic celiac patients (CD), CD patients with anemia and GFD treated CD with normalization of duodenal mucosa

2013-04-19 | GSE46201 | GEO

miRNA profiling of celiac disease

Project description:microRNAs were profiled in healthy controls, classic celiac patients (CD), CD patients with anemia and GFD treated CD with normalization of duodenal mucosa all CD conditions were related to controls. For each group, five patients were pooled. One replicate per experiment

2013-04-19 | E-GEOD-46201 | biostudies-arrayexpress

Expression analysis in intestinal mucosa of genes under association peaks in celiac disease

Project description:Celiac disease is a chronic immune-mediated disorder with an important genetic component. To date, there are 57 independent association signals from 39 non-HLA loci, and a total of 66 candidate genes have been proposed. We aimed to scrutinize the functional implication of 45 of those genes by analyzing their expression in the disease tissue of celiac patients (at diagnosis/treatment) compared to non-celiac controls. The sample set consisted of 15 CD children at diagnosis (on a gluten-containing diet, with CD associated antibodies, atrophy of intestinal villi and crypt hyperplasia), and the same patients in remission after being treated with GFD for >2 years (asymptomatic, antibody negative, and normalized intestinal epithelium at that time), plus 15 tissue samples from non-celiac individuals not suffering from inflammation at the time of endoscopy used as controls

2014-09-30 | E-GEOD-61849 | biostudies-arrayexpress

Comparison of intestinal surface CD3- refractory celiac disease type II (RCDII) cell lines with intestinal surface CD3+ cell lines of non-RCDII patients

2012-06-12 | GSE33078 | GEO

Non-Responding Celiac Disease

Project description:Non-Responding Celiac Disease

| PRJEB65879 | ENA

Comparison of intestinal surface CD3- refractory celiac disease type II (RCDII) cell lines with intestinal surface CD3+ cell lines of non-RCDII patients

Project description:Analysis of transcriptional differences between aberrant (surface CD3-) RCDII cell lines and regular (surface CD3+) intraepithelial cell lines in order to characterize aberrant RCDII cells. All cell lines were cultured from duodenal biopsies of RCDII or non-RCDII (either celiac or non-celiac) patients. We compared 3 RCDII cell lines from RCDII patients P1-P3 with the following control cell lines: CD3+CD4+ T cell line from P1 and P3, CD3+CD8+ T cell line from P3 and mixed CD4/CD8+ T cell lines from non-RCDII patients. All control cells matched the phenotype of mature T cells (CD3+CD4+ and/or CD3+CD8+). Samples were randomly distributed among two BeadChips and measured in duplicates.

2012-06-11 | E-GEOD-33078 | biostudies-arrayexpress

16S V3-V4 -based microbial profiling of duodenal mucosa samples obtained by esophagogastroduodenoscopy from patients affected by potential celiac disease and celiac disease

Project description:16S V3-V4 -based microbial profiling of duodenal mucosa samples obtained by esophagogastroduodenoscopy from patients affected by potential celiac disease and celiac disease

| PRJNA750525 | ENA

Transcription profiling of MIII celiac disease patients vs controls (M0) individuals

Project description:Comparison of MIII celiac disease patients to controls (M0) individuals.

2005-01-01 | E-MEXP-42 | biostudies-arrayexpress

Expression analysis in intestinal mucosa of genes under association peaks in celiac disease

2014-09-30 | GSE61849 | GEO