Ontology highlight
ABSTRACT:
ORGANISM(S): Halobacterium sp. NRC-1
SUBMITTER: Min Pan
PROVIDER: E-GEOD-7729 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Bonneau Richard R Facciotti Marc T MT Reiss David J DJ Schmid Amy K AK Pan Min M Kaur Amardeep A Thorsson Vesteinn V Shannon Paul P Johnson Michael H MH Bare J Christopher JC Longabaugh William W Vuthoori Madhavi M Whitehead Kenia K Madar Aviv A Suzuki Lena L Mori Tetsuya T Chang Dong-Eun DE Diruggiero Jocelyne J Johnson Carl H CH Hood Leroy L Baliga Nitin S NS
Cell 20071201 7
The environment significantly influences the dynamic expression and assembly of all components encoded in the genome of an organism into functional biological networks. We have constructed a model for this process in Halobacterium salinarum NRC-1 through the data-driven discovery of regulatory and functional interrelationships among approximately 80% of its genes and key abiotic factors in its hypersaline environment. Using relative changes in 72 transcription factors and 9 environmental factors ...[more]