Unknown,Transcriptomics,Genomics,Proteomics

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Comparative transcriptomics of Clostridium thermocellum wild type (Î?hpt) and Type I glutamine synthetase (Clo1313_2031) deletion strains using RNA-seq


ABSTRACT: RNA-seq analysis revealed that genes involved in urea uptake and metabolism were significantly upregulated in the Clo1313_2031 deletion strain, suggesting that deletion of Clo1313_2031 mimics nitrogen starvation in C. thermocellum. Additionally, genes encoding the RNF-complex were also more highly expressed and in turn may have a potential role in increasing ethanol production. Samples for RNA-seq were taken from mid-exponential phase (OD ~ 0.33) batch cultures grown in MTC on 4.5 g/l cellobiose

ORGANISM(S): Ruminiclostridium thermocellum DSM 1313

SUBMITTER: Dawn Klingeman 

PROVIDER: E-GEOD-78219 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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