MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Leonard Goldstein
PROVIDER: E-GEOD-7842 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype.
Blenkiron Cherie C Goldstein Leonard D LD Thorne Natalie P NP Spiteri Inmaculada I Chin Suet-Feung SF Dunning Mark J MJ Barbosa-Morais Nuno L NL Teschendorff Andrew E AE Green Andrew R AR Ellis Ian O IO Tavaré Simon S Caldas Carlos C Miska Eric A EA
Genome biology 20070101 10
<h4>Background</h4>MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants and animals, often act post-transcriptionally to inhibit gene expression.<h4>Results</h4>Here we report the analysis of miRNA expression in 93 primary human breast tumors, using a bead-based flow cytometric miRNA expression profiling method. Of 309 human miRNAs assayed, we identify 133 miRNAs expressed in human breast and breast tumors. We used mRNA expression profiling to classify the breast tumors as l ...[more]
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