Non-coding antisense transcription detected by conventional and single-stranded cDNA microarray
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ake Borg
PROVIDER: E-GEOD-7860 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Non-coding antisense transcription detected by conventional and single-stranded cDNA microarray.
Vallon-Christersson Johan J Staaf Johan J Kvist Anders A Medstrand Patrik P Borg Ake A Rovira Carlos C
BMC genomics 20070829
<h4>Background</h4>Recent studies revealed that many mammalian protein-coding genes also transcribe their complementary strands. This phenomenon raises questions regarding the validity of data obtained from double-stranded cDNA microarrays since hybridization to both strands may occur. Here, we wanted to analyze experimentally the incidence of antisense transcription in human cells and to estimate their influence on protein coding expression patterns obtained by double-stranded microarrays. Ther ...[more]
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