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RNAseq Reveals Virulence-Specific Host Responses to M. tuberculosis infection

ABSTRACT: We infect bone marrow derived macrophages (BMDMs) with either a Hyper or Hypovirulent Mycobacterium tuberculolsis strain and assess the host response to these bacteria through RNAseq Uninfected BMDMs served as controls, BMDMs infected with Hypervirulent M.tb (designated R55), BMDMs infected with Hypovirulent m.tb (designated R50). 3 groups with 3 biological replicates, each analysed in triplicate.

ORGANISM(S): Mus musculus

SUBMITTER: Gina Leiching

PROVIDER: E-GEOD-78706 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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