Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Eugene Oltz
PROVIDER: E-GEOD-78897 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Koues Olivia I OI Collins Patrick L PL Cella Marina M Robinette Michelle L ML Porter Sofia I SI Pyfrom Sarah C SC Payton Jacqueline E JE Colonna Marco M Oltz Eugene M EM
Cell 20160505 5
Innate lymphoid cells (ILCs) serve as sentinels in mucosal tissues, sensing release of soluble inflammatory mediators, rapidly communicating danger via cytokine secretion, and functioning as guardians of tissue homeostasis. Although ILCs have been extensively studied in model organisms, little is known about these "first responders" in humans, especially their lineage and functional kinships to cytokine-secreting T helper (Th) cell counterparts. Here, we report gene regulatory circuitries for fo ...[more]