Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Steve Cole
PROVIDER: E-GEOD-79269 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kohrt Brandon A BA Worthman Carol M CM Adhikari Ramesh P RP Luitel Nagendra P NP Arevalo Jesusa M G JM Ma Jeffrey J McCreath Heather H Seeman Teresa E TE Crimmins Eileen M EM Cole Steven W SW
Proceedings of the National Academy of Sciences of the United States of America 20160711 29
Adverse social conditions in early life have been linked to increased expression of proinflammatory genes and reduced expression of antiviral genes in circulating immune cells-the conserved transcriptional response to adversity (CTRA). However, it remains unclear whether such effects are specific to the Western, educated, industrialized, rich, and democratic (WEIRD) cultural environments in which previous research has been conducted. To assess the roles of early adversity and individual psycholo ...[more]