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Expression data of HBV infected liver tissue

ABSTRACT: We analyzed three clinical parameters with gene expression data from 122 liver tissues. Six healthy samples were used in validation. All hepatitis samples were HBV infected, which was validated by positive HBsAg or serum HBV-DNA. The samples with HCV infection or metabolic liver injury (e.g. fatty liver, chronic alcoholic hepatitis, etc.) were excluded. This dataset is part of the TransQST collection.

ORGANISM(S): Homo sapiens

SUBMITTER: Weichen Zhou

PROVIDER: E-GEOD-83148 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Predictive model for inflammation grades of chronic hepatitis B: Large-scale analysis of clinical parameters and gene expressions.

Zhou Weichen W Ma Yanyun Y Zhang Jun J Hu Jingyi J Zhang Menghan M Wang Yi Y Li Yi Y Wu Lijun L Pan Yida Y Zhang Yitong Y Zhang Xiaonan X Zhang Xinxin X Zhang Zhanqing Z Zhang Jiming J Li Hai H Lu Lungen L Jin Li L Wang Jiucun J Yuan Zhenghong Z Liu Jie J

Liver international : official journal of the International Association for the Study of the Liver 20170419 11

<h4>Background</h4>Liver biopsy is the gold standard to assess pathological features (eg inflammation grades) for hepatitis B virus-infected patients although it is invasive and traumatic; meanwhile, several gene profiles of chronic hepatitis B (CHB) have been separately described in relatively small hepatitis B virus (HBV)-infected samples. We aimed to analyse correlations among inflammation grades, gene expressions and clinical parameters (serum alanine amino transaminase, aspartate amino tran ...[more]

PMID: 28328162

Publication: 1/3

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