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Transcription profiling of rat extraocular and gastrocnemius/soleus muscles during postnatal development

ABSTRACT: Conserved and muscle group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype. Comparison of postnatal development of extraocular and hindlimb muscle between birth and P45.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Henry Kaminski

PROVIDER: E-GEOD-903 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Conserved and muscle-group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype.

Cheng Georgiana G Merriam Anita P AP Gong Bendi B Leahy Patrick P Khanna Sangeeta S Porter John D JD

Physiological genomics 20040708 2

Current models in skeletal muscle biology do not fully account for the breadth, causes, and consequences of phenotypic variation among skeletal muscle groups. The muscle allotype concept arose to explain frank differences between limb, masticatory, and extraocular (EOM) muscles, but there is little understanding of the developmental regulation of the skeletal muscle phenotypic range. Here, we used morphological and DNA microarray analyses to generate a comprehensive temporal profile for rat EOM ...[more]

PMID: 15138310

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