Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of hippocampus samples from the Rattus norvegicus Syracuse High Avoidance (SHA) and Syracuse Low Avoidance (SLA) strains


ABSTRACT: Comparisons of hippocampi of Syracuse High Avoidance (SHA) and Syracuse Low Avoidance (SLA) learning rats

ORGANISM(S): Rattus norvegicus

SUBMITTER: Shumin Zhang 

PROVIDER: E-GEOD-932 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Molecular correlates of emotional learning using genetically selected rat lines.

Zhang S S   Amstein T T   Shen J J   Brush F R FR   Gershenfeld H K HK  

Genes, brain, and behavior 20050301 2


The genetic contributions to active avoidance learning in rodents have been well established, yet the molecular basis for genetically selected line differences remains poorly understood. To identify candidate genes influencing this active avoidance paradigm, we utilized the bidirectionally selected Syracuse high- and low-avoidance (SHA and SLA) rat lines that markedly differ in their two-way active avoidance behavior. Rats were phenotyped, rested to allow recovery from testing stress and then hi  ...[more]

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