Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Ned Mantei
PROVIDER: E-GEOD-972 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Buchstaller Johanna J Sommer Lukas L Bodmer Matthias M Hoffmann Reinhard R Suter Ueli U Mantei Ned N
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040301 10
Schwann cells develop from multipotent neural crest stem cells and are important for neuronal survival, maintenance of axonal integrity, and myelination. We used transgenic mice expressing green fluorescent protein in a tissue-specific manner to isolate viable, pure populations of neural crest stem cells and developing Schwann cells, which are not readily accessible by microdissection. Starting with the minute amounts of RNA obtained, a two-round amplification procedure was used to achieve repro ...[more]