Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of Bacillus anthracis Sterne 34F2 cells and a sodA1 deletion mutant strain in reponse to different concentrations of paraquat and hydrogen peroxide

ABSTRACT: Bacillus anthracis Sterne 34F2 cells were grown in the absence of and in the presence of different concentrations of paraquat and hydrogen peroxide. Additionally, a deletion mutant strain lacking the sodA1 gene was also assayed with and without the addition of different concentrations of paraquat.

ORGANISM(S): Bacillus anthracis

SUBMITTER: Nicholas Bergman

PROVIDER: E-MEXP-1043 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The global transcriptional responses of Bacillus anthracis Sterne (34F2) and a Delta sodA1 mutant to paraquat reveal metal ion homeostasis imbalances during endogenous superoxide stress.

Passalacqua Karla D KD Bergman Nicholas H NH Lee Jung Yeop JY Sherman David H DH Hanna Philip C PC

Journal of bacteriology 20070323 11

Microarray analyses were conducted to evaluate the paraquat-induced global transcriptional response of Bacillus anthracis Sterne (34F(2)) to varying levels of endogenous superoxide stress. Data revealed that the transcription of genes putatively involved in metal/ion transport, bacillibactin siderophore biosynthesis, the glyoxalase pathway, and oxidoreductase activity was perturbed most significantly. A B. anthracis mutant lacking the superoxide dismutase gene sodA1 (Delta sodA1) had transcripti ...[more]

PMID: 17384197

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Dataset Information

Transcription profiling of Bacillus anthracis Sterne 34F2 cells and a sodA1 deletion mutant strain in reponse to different concentrations of paraquat and hydrogen peroxide

Publications

The global transcriptional responses of Bacillus anthracis Sterne (34F2) and a Delta sodA1 mutant to paraquat reveal metal ion homeostasis imbalances during endogenous superoxide stress.

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