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Transcription profiling of superior mesenteric arteries from rats that have had portal vein ligation or a sham procedure for different lengths of time


ABSTRACT: Twenty-four male Sprague-Dawley rats were used for this experiment, a partial portal vein ligadure (PVL) was carried out in 12 rats, the other 12 rats were sham-operated. Superior mesenteric artery (SMA) samples were sequentially obtained from 2 rats from the PVL and sham groups at 1, 6, and 24 hours, and 3, 5 and 14 days after portal vein ligation or sham procedure. Each PVL sample was paired with its corresponding sham sample using a dye swap experiment design (technical replicates) resulting in 12 arrays (6 time points x 2 dye swap).

INSTRUMENT(S): GenePix 4000A [Axon Instruments]

ORGANISM(S): Rattus norvegicus

DISEASE(S): portal hypertension

SUBMITTER: Mar Coll 

PROVIDER: E-MEXP-1107 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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