Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: pierre close
PROVIDER: E-MEXP-1220 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Buytaert E E Matroule J Y JY Durinck S S Close P P Kocanova S S Vandenheede J R JR de Witte P A PA Piette J J Agostinis P P
Oncogene 20071022 13
Photodynamic therapy (PDT) is an anticancer approach utilizing a light-absorbing molecule and visible light irradiation to generate, in the presence of O(2), cytotoxic reactive oxygen species, which cause tumor ablation. Given that the photosensitizer hypericin is under consideration for PDT treatment of bladder cancer we used oligonucleotide microarrays in the T24 bladder cancer cell line to identify differentially expressed genes with therapeutic potential. This study reveals that the expressi ...[more]