Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human mesenchymal stem cells from adipose tissue grown in normal media in monolayer or with LVG or RGD alignate


ABSTRACT: Experiment to see the effect of regular and RGD alginate on MSC derived from bone marrow and adipose tissue

ORGANISM(S): Homo sapiens

SUBMITTER: Shivali Duggal 

PROVIDER: E-MEXP-1273 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds.

Duggal Shivali S   Frønsdal Katrine B KB   Szöke Krisztina K   Shahdadfar Aboulghassem A   Melvik Jan Egil JE   Brinchmann Jan E JE  

Tissue engineering. Part A 20090701 7


Human mesenchymal stem cells (MSC) are popular candidates for tissue engineering. MSC are defined by their properties in two-dimensional (2D) culture systems. Cells in 2D are known to differ from their in vivo counterparts in cell shape, proliferation, and gene expression. Little is so far known about the phenotype and gene expression of cells in three-dimensional (3D) culture systems. To begin to unravel the impact of 3D versus 2D culture conditions on MSC, we have established MSC from adipose  ...[more]

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