Transcription profiling of rat carotid artery following arteriotomy
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Pietro Zoppoli
PROVIDER: E-MEXP-1278 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Expression profiles in surgically-induced carotid stenosis: a combined transcriptomic and proteomic investigation.
Forte A A Finicelli M M De Luca P P Quarto C C Onorati F F Santè P P Renzulli A A Galderisi U U Berrino L L De Feo M M Rossi F F Cotrufo M M Cascino A A Cipollaro M M
Journal of cellular and molecular medicine 20081001 5B
Vascular injury aimed at stenosis removal induces local reactions often leading to restenosis. The aim of this study was a concerted transcriptomic-proteomics analysis of molecular variations in a model of rat carotid arteriotomy, to dissect the molecular pathways triggered by vascular surgical injury and to identify new potential anti-restenosis targets. RNA and proteins extracted from inbred Wistar Kyoro (WKY) rat carotids harvested 4 hrs, 48 hrs and 7 days after arteriotomy were analysed by A ...[more]
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