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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of normal, tumor and pure stromal tissue samples from patients with prostate adenocarcinoma, together with 4 cell lines

ABSTRACT: We have used normal, tumoral and pure stromal whole tissue samples, and cells lines in order to identify new markers of prostate cancer.
The normal, tumoral and stromal tissue were obtained from patients diagnosed with prostate adenocarcinoma.

ORGANISM(S): Homo sapiens

DISEASE(S): adenocarcinoma

SUBMITTER: Timothy Thomson

PROVIDER: E-MEXP-1331 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer.

Bermudo Raquel R Abia David D Ferrer Berta B Nayach Iracema I Benguria Alberto A Zaballos Angel A del Rey Javier J Miró Rosa R Campo Elías E Martínez-A Carlos C Ortiz Angel R AR Fernández Pedro L PL Thomson Timothy M TM

BMC cancer 20081030

<h4>Background</h4>Transcriptional profiling of prostate cancer (PC) has unveiled new markers of neoplasia and allowed insights into mechanisms underlying this disease. Genomewide analyses have also identified new chromosomal abnormalities associated with PC. The combination of both classes of data for the same sample cohort might provide better criteria for identifying relevant factors involved in neoplasia. Here we describe transcriptional signatures identifying distinct normal and tumoral pro ...[more]

PMID: 18973659

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Project description:Comparison of microRNA expression HeLa cells in hypoxia or normoxia

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