Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling by array and functional characterization of developing cardiomyocytes from recombinant murine embryonic stem cells

ABSTRACT: Here, we characterize the transcriptome of the mouse embryonic stem cell line CM7-1 during differentiation into beating cardiomyocytes and compared the gene expression profiles with those from primary adult murine cardiomyocytes and left ventricular myocardium.

ORGANISM(S): Mus musculus

SUBMITTER: Michael Seewald

PROVIDER: E-MEXP-1405 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genomic profiling of developing cardiomyocytes from recombinant murine embryonic stem cells reveals regulation of transcription factor clusters.

Seewald Michael J MJ Ellinghaus Peter P Kassner Astrid A Stork Ines I Barg Martina M Niebrügge Sylvia S Golz Stefan S Summer Holger H Zweigerdt Robert R Schräder Eva-Maria EM Feicht Samantha S Jaquet Kornelia K Reis Stephanie S Körfer Reiner R Milting Hendrik H

Physiological genomics 20090317 1

Cardiomyocytes derived from pluripotent embryonic stem cells (ESC) have the advantage of providing a source for standardized cell cultures. However, little is known on the regulation of the genome during differentiation of ESC to cardiomyocytes. Here, we characterize the transcriptome of the mouse ESC line CM7/1 during differentiation into beating cardiomyocytes and compare the gene expression profiles with those from primary adult murine cardiomyocytes and left ventricular myocardium. We observ ...[more]

PMID: 19293330

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Dataset Information

Transcription profiling by array and functional characterization of developing cardiomyocytes from recombinant murine embryonic stem cells

Publications

Genomic profiling of developing cardiomyocytes from recombinant murine embryonic stem cells reveals regulation of transcription factor clusters.

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