Dataset Information
Transcription profiling of pancreas from patients suffering cancer (malignant tumors) and controls (benign tumors)
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): benign tumor
SUBMITTER: Nicolas Cagnard
PROVIDER: E-MEXP-1914 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression profiling provides insights into the pathways involved in solid pseudopapillary neoplasm of the pancreas.
The Journal of pathology 20090601 2
Solid-pseudopapillary neoplasms (SPNs) are rare human pancreatic neoplasms usually associated with a good prognosis. In contrast to other pancreatic tumours, aberrant activation of the Wnt-beta-catenin pathway appears to be a constant feature in SPN. Aside from activation of the Wnt-beta-catenin pathway, little is known about biological pathways deregulated in SPN. We carried out transcriptome profiling of SPN to gain insights into the pathogenesis of these tumours. As expected, the over-express ...[more]
