Dataset Information
Transcription profiling of Salmonella enteritidisto determine the effect of the absence of GGDEF proteins on the transcriptional pattern
Ontology highlight
ABSTRACT:
ORGANISM(S): Salmonella enteritidis
SUBMITTER: Iñigo Lasa
PROVIDER: E-MEXP-2067 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella.
Proceedings of the National Academy of Sciences of the United States of America 20090428 19
Bacteria have developed an exclusive signal transduction system involving multiple diguanylate cyclase and phosphodiesterase domain-containing proteins (GGDEF and EAL/HD-GYP, respectively) that modulate the levels of the same diffusible molecule, 3'-5'-cyclic diguanylic acid (c-di-GMP), to transmit signals and obtain specific cellular responses. Current knowledge about c-di-GMP signaling has been inferred mainly from the analysis of recombinant bacteria that either lack or overproduce individual ...[more]
