Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Schistosoma lifecycle


ABSTRACT: Transcriptome analysis throughout the lifecycle of the helminth Schistosoma mansoni.

ORGANISM(S): Schistosoma mansoni

SUBMITTER: Jennifer Fitzpatrick 

PROVIDER: E-MEXP-2094 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses.

Fitzpatrick Jennifer M JM   Peak Emily E   Perally Samirah S   Chalmers Iain W IW   Barrett John J   Yoshino Timothy P TP   Ivens Alasdair C AC   Hoffmann Karl F KF  

PLoS neglected tropical diseases 20091103 11


<h4>Background</h4>Novel methods to identify anthelmintic drug and vaccine targets are urgently needed, especially for those parasite species currently being controlled by singular, often limited strategies. A clearer understanding of the transcriptional components underpinning helminth development will enable identification of exploitable molecules essential for successful parasite/host interactions. Towards this end, we present a combinatorial, bioinformatics-led approach, employing both stati  ...[more]

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