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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Schistosoma lifecycle

ABSTRACT: Transcriptome analysis throughout the lifecycle of the helminth Schistosoma mansoni.

ORGANISM(S): Schistosoma mansoni

SUBMITTER: Jennifer Fitzpatrick

PROVIDER: E-MEXP-2094 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses.

Fitzpatrick Jennifer M JM Peak Emily E Perally Samirah S Chalmers Iain W IW Barrett John J Yoshino Timothy P TP Ivens Alasdair C AC Hoffmann Karl F KF

PLoS neglected tropical diseases 20091103 11

<h4>Background</h4>Novel methods to identify anthelmintic drug and vaccine targets are urgently needed, especially for those parasite species currently being controlled by singular, often limited strategies. A clearer understanding of the transcriptional components underpinning helminth development will enable identification of exploitable molecules essential for successful parasite/host interactions. Towards this end, we present a combinatorial, bioinformatics-led approach, employing both stati ...[more]

PMID: 19885392

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