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Individual bee brain behavior-age

ABSTRACT: This experiment examines gene expression profiles in individual honey bee brains (adult worker Apis mellifera). The purpose is to test whether behavioral phenotype can be predicted by expression profiles in individual brains in a naturalistic context (i.e., colonies in the field). The two behavioral phenotypes examined are 'nurse' and 'forager'. Other factors examined are age, genotype (full-sister group), and colony environment.

An additional processed data file is available on the FTP site for this experiment.

ORGANISM(S): Apis mellifera

SUBMITTER: Charles Whitfield

PROVIDER: E-MEXP-24 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiles in the brain predict behavior in individual honey bees.

Whitfield Charles W CW Cziko Anne-Marie AM Robinson Gene E GE

Science (New York, N.Y.) 20031001 5643

We show that the age-related transition by adult honey bees from hive work to foraging is associated with changes in messenger RNA abundance in the brain for 39% of approximately 5500 genes tested. This result, discovered using a highly replicated experimental design involving 72 microarrays, demonstrates more extensive genomic plasticity in the adult brain than has yet been shown. Experimental manipulations that uncouple behavior and age revealed that messenger RNA changes were primarily associ ...[more]

PMID: 14551438

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