Transcription profiling of mouse cardiac muscle and epicardium after left coronary artery ligation and sharm operation.
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Lars Bochmann
PROVIDER: E-MEXP-2446 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Revealing new mouse epicardial cell markers through transcriptomics.
Bochmann Lars L Sarathchandra Padmini P Mori Federica F Lara-Pezzi Enrique E Lazzaro Domenico D Rosenthal Nadia N
PloS one 20100628 6
<h4>Background</h4>The epicardium has key functions during myocardial development, by contributing to the formation of coronary endothelial and smooth muscle cells, cardiac fibroblasts, and potentially cardiomyocytes. The epicardium plays a morphogenetic role by emitting signals to promote and maintain cardiomyocyte proliferation. In a regenerative context, the adult epicardium might comprise a progenitor cell population that can be induced to contribute to cardiac repair. Although some genes in ...[more]
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