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Unknown,Transcriptomics,Genomics,Proteomics

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Henry PGYP1

ABSTRACT: Wolbachia pipientis is an obligate intracellular bacterium capable of spreading itself through populations by manipulating the reproduction of its hosts. The Wolbachia strain wMelPop, which reduces longevity in Drosophila melanogaster, has been introduced into the Dengue virus mosquito vector, Aedes aegypti, as a strategy to reduce disease transmission. The infecting Wolbachia halve the lifespan of the mosquito and induce numerous behavioral and physiological abnormalities that reduce the ability of the mosquito to successfully obtain a blood meal. We aim to understand the mechanism underpinning these changes and hence have chosen to explore how Wolbachia may be interacting with the insects nervous and muscle tissue. We carried out a series whole genome profiling experiments based on head and muscle tissues to identify mosquito pathways affected by the microbe.

ORGANISM(S): Aedes aegypti

DISEASE(S): Wolbachia infected

SUBMITTER: Henry Ye

PROVIDER: E-MEXP-2907 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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