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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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MRNA expression profile of medullary thymic epithelial cells - mTECs - from pre-diabetic NOD mice

ABSTRACT: The oligo microarrays were used to determine mRNA expression profiles of medullary thymic epithelial cells (mTECs) isolated from thymus of pre-diabetic NOD mice.

ORGANISM(S): Mus musculus

SUBMITTER: Geraldo Passos

PROVIDER: E-MEXP-3358 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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microRNA expression profile from medullary thymic epithelial cells - mTECs - from pre-diabetic NOD mice

Project description:Due to high sequence identity between human and M. musculus microRNAs, we used in this study human microRNA microarrays to determine microRNA expression profiles of medullary thymic epithelial cells (mTECs) from thymus of pre-diabetic NOD mice.

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Development of type 1 diabetes mellitus T1D in NOD mice follows transcriptional activity of thymocytes and peripheral T lymphocytes

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Project description:The oligo microarrays were used to determine microRNA expression profiles of medullary thymic epithelial cells (mTECs) submitted of in vitro Aire Knockdown (siRNA silencing).

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