Transcription profiling by array of serum microRNAs in rat livers to screen for specific biomarkers to be used in diagnosis of compound- and herb-induced liver injury.

ABSTRACT: In this study, we employed a strategy to screen miRNA expression profiles in liver tissue by miRCURY LNA(tm) microRNA array analysis followed by TaqMan probe-based quantitative reverse transcription-PCR (qRT-PCR) to validate the miRNA expression profiles in serum and liver of two parallel rat drug-induced liver injury (DILI) models induced by a compound (acetaminophen, APAP) or an herb (Dioscorea bulbifera, DB).

ORGANISM(S): Rattus norvegicus

SUBMITTER: Yuwen Su 

PROVIDER: E-MEXP-3364 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress