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B. cenocepacia transcriptome in vivo

ABSTRACT: The adaptation of B. cenocepacia to the host environment was assessed in a rat chronic respiratory infection model and compared to that of high cell-density in vitro-grown cultures using transcriptomics

ORGANISM(S): Burkholderia cenocepacia

SUBMITTER: Eoin O'Grady

PROVIDER: E-MEXP-3367 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Burkholderia cenocepacia differential gene expression during host-pathogen interactions and adaptation to the host environment.

O'Grady Eoin P EP Sokol Pamela A PA

Frontiers in cellular and infection microbiology 20111209

Members of the Burkholderia cepacia complex (Bcc) are important in medical, biotechnological, and agricultural disciplines. These bacteria naturally occur in soil and water environments and have adapted to survive in association with plants and animals including humans. All Bcc species are opportunistic pathogens including Burkholderia cenocepacia that causes infections in cystic fibrosis and chronic granulomatous disease patients. The adaptation of B. cenocepacia to the host environment was ass ...[more]

PMID: 22919581

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