Microbiota regualtion of miRNA

ABSTRACT: This experiment was investigating how gut commensal bacteria and intestinal inflammation affect miRNA expression. We analyzed miRNA expression of spleen and intestine from specific pathogen free (SPF) B6 mice, germ-free (GF) B6 mice, and IL-10 knockout mice which have severe colitis by microarray. Thus we have total 6 samples: GF spleen; GF intestines; SPF spleen; SPF intestine; IL-10 KO spleen and IL-10 KO intestine. We directly isolated RNA from whole spleens or intestines without any treatments, and then did microarray analysis.

ORGANISM(S): Mus musculus

DISEASE(S): germ-free

SUBMITTER: yingzi cong 

PROVIDER: E-MEXP-3406 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress