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Whole blood transcriptome alteration between pigs with extreme in vivo dsRNA-induced serum interferon-alpha production

ABSTRACT: The interferon (IFN) is a major effector of the innate immunity which mediates an adaptive immune response against broad spectrum pathogens. The aim of this work has been to investigate the differences of the virus mimic dsRNA (Poly I:C)-inducted in vivo transcriptomic alteration between pigs with high (HIGH) and low (LOW) serum interferon-alpha production. The pigs with extreme yield of induced interferon-alpha from a F2 resource population were selected for whole blood gene expression analysis using the porcine Affymetrix microarray

ORGANISM(S): Sus scrofa

SUBMITTER: Xiangdong Liu

PROVIDER: E-MEXP-3452 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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