MiR-146a target identification in gastric cancer

ABSTRACT: We have found expression of miR-146a up-regulated in gastric cancer. To identify new targets of miR-146a we profiled the transcriptome after miR-146a over-expression in the human gastric cancer cell line SNU638. SNU638 cells were transfected in triplicates with 50 nM miR-146a or control (siGlo) using Lipofectamine 2000. Total RNA was harvested 24 h after transfection using Trizol reagent. There are a total of six arrays included in this experiment, including three biological replicates of mRNA expression after miR-146a over-expression and three controls in SNU638 cells.

ORGANISM(S): Homo sapiens

SUBMITTER: Stephanie Crone 

PROVIDER: E-MEXP-3479 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress