Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Maria Foti
PROVIDER: E-MEXP-3489 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Spiering Rachel R van der Zee Ruurd R Wagenaar Josée J Kapetis Dimos D Zolezzi Francesca F van Eden Willem W Broere Femke F
PloS one 20120925 9
Tolerogenic dendritic cells (DCs) can induce regulatory T cells and dampen pathogenic T cell responses. Therefore, they are possible therapeutic targets in autoimmune diseases. In this study we investigated whether mouse tolerogenic DCs are induced by the phytonutrient carvacrol, a molecule with known anti-inflammatory properties, in combination with a physiological stress. We show that treatment of DCs with carvacrol and thermal stress led to the mRNA expression of both pro- and anti-inflammato ...[more]