Loor-Mouse-mammary transcriptomics
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Juan Loor
PROVIDER: E-MEXP-3622 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue.
Kadegowda Anil K G AK Khan M Jawad MJ Piperova Liliana S LS Teter Beverly B BB Rodriguez-Zas Sandra L SL Erdman Richard A RA Loor Juan J JJ
Journal of lipids 20130514
Exogenous trans-10, cis-12-CLA (CLA) reduces lipid synthesis in murine adipose and mammary (MG) tissues. However, genomewide alterations in MG and liver (LIV) associated with dietary CLA during lactation remain unknown. We fed mice (n = 5/diet) control or control + trans-10, cis-12-CLA (37 mg/day) between d 6 and d 10 postpartum. The 35,302 annotated murine exonic evidence-based oligo (MEEBO) microarray and quantitative RT-PCR were used for transcript profiling. Milk fat concentration was 44% lo ...[more]
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