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Ada2b isoforms

ABSTRACT: Gene expression profiling of the two ADA2b protein (ADA2bS and ADA2bL) in Drosophila melanogaster

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Tibor Pankotai

PROVIDER: E-MEXP-3747 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Functional characterization and gene expression profiling of Drosophila melanogaster short dADA2b isoform-containing dSAGA complexes.

Pankotai Tibor T Zsindely Nóra N Vamos Edith E EE Komonyi Orbán O Bodai László L Boros Imre M IM

BMC genomics 20130122

<h4>Background</h4>ADA2 proteins, together with ADA3, SGF29 and GCN5 form the acetyltransferase module of GNAT-type histone acetyltransferase complexes. ADA2b is present in the SAGA complex, which plays roles in various chromatin-related processes via histone H3 modifications and by other mechanisms.<h4>Results</h4>In this report we present findings showing that during Drosophila melanogaster development two dADA2b isoforms (dADA2bS and dADA2bL) - which differ in their C-terminal domains - are e ...[more]

PMID: 23336284

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