Ontology highlight
ABSTRACT:
colorectal cancer patients after colonoscopy. The aim of this study is to determine how significant the colonoscopy procedure may impact the global gene expression in human peripheral blood, and whether this colonoscopy induced variability would bias the biomarker research for colorectal cancer early detection.
ORGANISM(S): Homo sapiens
SUBMITTER: Qinghua Xu
PROVIDER: E-MEXP-3756 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Xu Ye Y Xu Qinghua Q Yang Li L Liu Fang F Ye Xun X Wu Fei F Ni Shujuan S Tan Cong C Cai Guoxiang G Meng Xia X Cai Sanjun S Du Xiang X
PloS one 20130501 5
Colorectal cancer is the leading cause of cancer-related deaths worldwide. The disease is curable when detected at an early stage. However, the compliance rate with current screening recommendations remains poor. An accurate, minimally invasive blood test that has the potential for greater patient compliance would be a welcome addition to the current methods. Recent data have shown that gene expression profile of peripheral blood cells can reflect disease states and thus have diagnostic value. I ...[more]