Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptomic evaluation for human health risks in a drinking water plant


ABSTRACT: In this study, we intended to use trans-omics approach and some clinical examinations to systematically evaluate the human health risks of source of drinking water, effluent of conventional treatment and effluent of advanced treatment by quaternized magnetic microsphere in a drinking water plant.

ORGANISM(S): Mus musculus

SUBMITTER: Peng Shi 

PROVIDER: E-MEXP-3766 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

A cross-omics toxicological evaluation of drinking water treated with different processes.

Shi Peng P   Jia Shuyu S   Zhang Xu-Xiang XX   Zhao Fuzheng F   Chen Yajun Y   Zhou Qing Q   Cheng Shupei S   Li Ai-Min AM  

Journal of hazardous materials 20140215


Cross-omics profiling and phenotypic analysis were conducted to comprehensively assess the toxicities of source of drinking water (SDW), effluent of conventional treatment (ECT) and effluent of advanced treatment (EAT) in a water treatment plant. SDW feeding increased body weight, and relative liver and kidney weights of mice. Hepatic histopathological damages and serum biochemical alterations were observed in the mice fed with SDW and ECT, but EAT feeding showed no obvious effects. Transcriptom  ...[more]

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