Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Dietmar Pfeifer
PROVIDER: E-MEXP-3807 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Leonhardt Franziska F Grundmann Sebastian S Behe Martin M Bluhm Franziska F Dumont Rebecca A RA Braun Friederike F Fani Melpomeni M Riesner Katarina K Prinz Gabriele G Hechinger Anne-Kathrin AK Gerlach Ulrike V UV Dierbach Heide H Penack Olaf O Schmitt-Gräff Annette A Finke Jürgen J Weber Wolfgang A WA Zeiser Robert R
Blood 20130117 17
Acute graft-versus-host disease (GvHD) is a complex process involving endothelial damage and neovascularization. Better understanding of the pathophysiology of neovascularization during GvHD could help to target this process while leaving T-cell function intact. Under ischemic conditions, neovascularization is regulated by different micro RNAs (miRs), which potentially play a role in inflamed hypoxic GvHD target organs. We observed strong neovascularization in the murine inflamed intestinal trac ...[more]