Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Integrated analysis of copy number variation and genome-wide expression profiling in colorectal cancer using macrodissected tissues


ABSTRACT: The experiment was to elucidate the association between copy number variation (CNV) and gene expression in colorectal cancer (CRC) samples and their corresponding non-cancerous tissues.

ORGANISM(S): Homo sapiens

SUBMITTER: Norfilza Mokhtar 

PROVIDER: E-MEXP-3980 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Integrated analysis of copy number variation and genome-wide expression profiling in colorectal cancer tissues.

Ali Hassan Nur Zarina NZ   Mokhtar Norfilza Mohd NM   Kok Sin Teow T   Mohamed Rose Isa I   Sagap Ismail I   Harun Roslan R   Jamal Rahman R  

PloS one 20140402 4


Integrative analyses of multiple genomic datasets for selected samples can provide better insight into the overall data and can enhance our knowledge of cancer. The objective of this study was to elucidate the association between copy number variation (CNV) and gene expression in colorectal cancer (CRC) samples and their corresponding non-cancerous tissues. Sixty-four paired CRC samples from the same patients were subjected to CNV profiling using the Illumina HumanOmni1-Quad assay, and validatio  ...[more]

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