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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Integrated analysis of copy number variation and genome-wide expression profiling in colorectal cancer using macrodissected tissues

ABSTRACT: The experiment was to elucidate the association between copy number variation (CNV) and gene expression in colorectal cancer (CRC) samples and their corresponding non-cancerous tissues.

ORGANISM(S): Homo sapiens

SUBMITTER: Norfilza Mokhtar

PROVIDER: E-MEXP-3980 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Integrated analysis of copy number variation and genome-wide expression profiling in colorectal cancer tissues.

Ali Hassan Nur Zarina NZ Mokhtar Norfilza Mohd NM Kok Sin Teow T Mohamed Rose Isa I Sagap Ismail I Harun Roslan R Jamal Rahman R

PloS one 20140402 4

Integrative analyses of multiple genomic datasets for selected samples can provide better insight into the overall data and can enhance our knowledge of cancer. The objective of this study was to elucidate the association between copy number variation (CNV) and gene expression in colorectal cancer (CRC) samples and their corresponding non-cancerous tissues. Sixty-four paired CRC samples from the same patients were subjected to CNV profiling using the Illumina HumanOmni1-Quad assay, and validatio ...[more]

PMID: 24694993

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