Transcription profiling of Drosophila of wild type migratory border cells (WTBC), non-migrating slbo mutant border cells (slboBC) and non-migrating follicle cells (FC)
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Pernille Rorth
PROVIDER: E-MEXP-493 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Systematic analysis of the transcriptional switch inducing migration of border cells.
Borghese Lodovica L Fletcher Georgina G Mathieu Juliette J Atzberger Ann A Eades William C WC Cagan Ross L RL Rørth Pernille P
Developmental cell 20060401 4
Cell migration within a natural context is tightly controlled, often by specific transcription factors. However, the switch from stationary to migratory behavior is poorly understood. Border cells perform a spatially and temporally controlled invasive migration during Drosophila oogenesis. Slbo, a C/EBP family transcriptional activator, is required for them to become migratory. We purified wild-type and slbo mutant border cells as well as nonmigratory follicle cells and performed comparative who ...[more]
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