Ontology highlight
ABSTRACT:
INSTRUMENT(S): G2565BA DNA microarray scanner [Agilent]
ORGANISM(S): Mus musculus
SUBMITTER: Susan Shinton
PROVIDER: E-MEXP-559 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Rumfelt Lynn L LL Zhou Yan Y Rowley Benjamin M BM Shinton Susan A SA Hardy Richard R RR
The Journal of experimental medicine 20060227 3
We describe here three CD19- B cell precursor populations in mouse bone marrow identified using 12-color flow cytometry. Cell transfer experiments indicate lineage potentials consistent with multilineage progenitor (MLP), common lymphoid progenitor (CLP), and B lineage-restricted pre-pro-B (Fr. A), respectively. However, single cell in vitro assays reveal lineage plasticity: lymphoid/myeloid lineage potential for CLP and B/T lineage potential for Fr. A. Despite myeloid potential, recombination a ...[more]