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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of transcription factor CREM deficient mice to assess its role in beta1-aderenoceptor-mediated detrimental cardiac effects

ABSTRACT: To assess a potential role of transcription factor CREM in the long-term detrimental effects of beta1-adrenoceptor overexpression, four mouse lines were generated and studied: wild-type mice (WT), Crem-normal beta1AR-transgenic mice (beta1ARTG), Crem-deficient non-transgenic mice (Crem-/-) and Crem-deficient beta1AR-transgenic mice (beta1ARTG/Crem-/-). We focused on genes up- or down-regulated in transgenic mice due to the lacking of CREM (beta1ARTG/Crem-/- vs. beta1ARTG).

ORGANISM(S): Mus musculus

SUBMITTER: Frank Müller

PROVIDER: E-MEXP-582 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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