Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of S. cerevisiae strains with controlled expression of hmo1 and Ifh1

ABSTRACT: Effect of hmo1 on yeast transcriptional response, as compared to Ifh1

INSTRUMENT(S): GenePix 4000A [Axon Instruments]

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Olivier GADAL

PROVIDER: E-MEXP-651 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription.

Berger Axel B AB Decourty Laurence L Badis Gwenaël G Nehrbass Ulf U Jacquier Alain A Gadal Olivier O

Molecular and cellular biology 20070917 22

Ribosome biogenesis requires equimolar amounts of four rRNAs and all 79 ribosomal proteins (RP). Coordinated regulation of rRNA and RP synthesis by eukaryotic RNA polymerases (Pol) I, III, and II is a key requirement for growth control. Using a novel global genetic approach, we showed that the absence of Hmo1 becomes lethal when combined with mutations of components of either the RNA Pol II or Pol I transcription machineries, of specific RP, or of the TOR pathway. Hmo1 directly interacts with bo ...[more]

PMID: 17875934

Similar Datasets

Transcription profiling of thermosensitive exosome mutants from permissive temperature and various time exposure to restrictive temperature

Project description:Transcriptome analyses of thermosensitive exosome mutants from permissive temperature to various time exposure to restrictive temperature.

2006-02-28 | E-MEXP-537 | biostudies-arrayexpress

Transcription profiling of Candida albicans in response to malachite green

Project description:This work aimed at analysing the transcriptome response of C. albicans wild type strain to three different doses of malachite green, inoculated for four different time periods.

2010-04-01 | E-TABM-893 | biostudies-arrayexpress

Transcription profiling of response to selenite of yeast strains that are wild type or deleted for transcription factor encoding genes involved in stress responses

Project description:This work aimed at analysing the transcriptome response of S. cerevisiae strains, wild type or deleted for transcription factor encoding genes involved in stress response, to selenite (1mM), inoculated for different time periods.

2008-03-14 | E-TABM-439 | biostudies-arrayexpress

Transcription profiling of S. cerevisiae and C. albicans wild type strains or strains deleted for transcription factor encoding genes involved in pleiotropic drug resistance after treatment with different doses of progesterone

Project description:This work aimed at analysing the transcriptome response of S. cerevisiae and C. albicans strains, wild type or deleted for transcription factor encoding genes involved in pleiotropic drug resistance, to three different doses of progesterone, inoculated for three different time periods.

2007-11-13 | E-TABM-345 | biostudies-arrayexpress

Chromatin immunoprecipitation to identify gene-nuclear pore association in wild type and THO mutants of yeast

Project description:This work aimed at analysing the genomic loci that are aberrantly docked to the nucleopore in mutants of the THO complex

2008-08-15 | E-TABM-535 | biostudies-arrayexpress

Chromatin immunoprecipitation of yeast to identify Yap1p binding in response to hydrogen peroxide and selenite treatment

Project description:This work aimed at analysing the Yap1p genome-wide location in different physiological conditions.

2008-03-05 | E-TABM-437 | biostudies-arrayexpress

Transcription profiling of honey bee queens treated with carbon dioxide and physical manipulation vs virgin controls

Project description:Mating is a complex process that causes many behavioral and physiological changes, but the factors triggering these changes and the underlying molecular processes are not well characterized. Honey bee queens provide a convenient system for dissecting these factors (e.g., physical manipulation, insemination volume, insemination substance) via instrumental insemination. We examined the effects of carbon dioxide (CO2), a commonly used anesthetic in instrumental insemination that causes changes similar to those observed after mating, and physical manipulation, which presumably mimics the act of copulation, on the brain transcriptional changes in honey bee queens. We found significant gene overlap between our study and previous mating studies in honey bee queens and Drosophila. This suggests that molecular pathways regulating the mating process are conserved across different mating regimes of honey bees as well as across insect orders.

2011-01-30 | E-MEXP-2646 | biostudies-arrayexpress

cGMP modulates responses to queen mandibular pheromone in worker honey bees

Project description:Responses to social cues, such as pheromones, can be modified by genotype, physiology, or environmental context. Honey bee queens produce a pheromone (queen mandibular pheromone; QMP) which regulates many aspects of worker bee behavior and physiology. Forager honey bees are less responsive to QMP than young nurse bees engaged in brood care, suggesting that physiological changes associated with behavioral maturation may modulate response to this pheromone. Since cGMP is a major regulator of behavioral maturation in honey bee workers, we examined its role in modulating worker responses to QMP. Treatment with a cGMP analog, 8-Br-cGMP, resulted in significant reductions in both behavioral and physiological responses to QMP in young caged workers. Treatment significantly reduced attraction to QMP (the retinue response) and inhibited the QMP-mediated increase in vitellogenin levels in the fat bodies of worker bees. Genome-wide analysis of brain gene expression patterns demonstrated that cGMP has a larger effect on expression levels than QMP, and that QMP has specific effects in the presence of cGMP, suggesting that some responses to QMP may be dependent on an individual beesM-^R physiological state. Several functional gene categories were significantly differentially expressed, including genes involved in regulating GTPase activity, phototransduction, immunity, and carboxylic acid transmembrane transporter activity. Overall, our data suggest that cGMP-mediated processes play a large role in modulating responses to queen pheromone in honey bees, at the behavioral, physiological and molecular levels.

2011-06-15 | E-MEXP-3135 | biostudies-arrayexpress

Transcription profiling of Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males)

Project description:Baseline gene expression in circulating peripheral blood mononuclear cells isolated from 18 apparently healthy volunteers (10 females and 8 males). The volunteers fasted overnight for 10 hours prior to collection of blood samples (but they were allowed water). 5 blood samples were collected from each volunteer at consecutive 8-day intervals. Volunteers were included in this study provided they met the following selection criteria, that they should be ?Aged between 20 and 45 years of age; ?A non-smoker (or an ex-smoker); ?Not pregnant or been pregnant in the last 12 months ?Not diagnosed with any long-term medical condition; ?Or have not (in the previous 4 months) donated blood, received any inoculations and are not taking regular prescribed medicine (including HRT and oral contraception) Prior to inclusion in this study volunteers were screened for general health and had a blood sample taken for routine screening of Hb content etc. Only those volunteers who were in good general health were allowed to participate in the study. The age of all volunteers has been reported here as being 20-45 years in order to preserve the anonymity of the data, and so that the individuals involved may not be able to track down their own specific data. Please contact us if the details of volunteers' ages are required.

2013-01-30 | E-TABM-7 | biostudies-arrayexpress

Impact of Nosema apis infection on worker honey bee fat body gene expression

Project description:Newly emerged adult workers (24 hours old) were infected with 50,000 Nosema apis spores in sucrose solution. Controls were fed sucrose. Workers were maintained in cages in an incubator and collected at 2 and 7 days post-infection. Fat body tissue was dissected (eviscerated abdomen) and whole genome expression in this tissue was compared across treatments and collection time points using microarrays.

2014-05-03 | E-MEXP-3892 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data