Dataset Information
Transcription profiling of FNR transcriptional regulator and NarP response regulator knock-out strains of Neisseria gonorrhoeae
Ontology highlight
ABSTRACT:
INSTRUMENT(S): ScanArray Express HT, ScanArray Express HT [PerkinElmer]
ORGANISM(S): Neisseria gonorrhoeae
SUBMITTER: Ying Li
PROVIDER: E-MEXP-726 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Coordinated regulation of the Neisseria gonorrhoeae-truncated denitrification pathway by the nitric oxide-sensitive repressor, NsrR, and nitrite-insensitive NarQ-NarP.
The Journal of biological chemistry 20060905 44
Neisseria gonorrhoeae survives anaerobically by reducing nitrite to nitrous oxide catalyzed by the nitrite and nitric oxide reductases, AniA and NorB. P(aniA) is activated by FNR (regulator of fumarate and nitrate reduction), the two-component regulatory system NarQ-NarP, and induced by nitrite; P(norB) is induced by NO independently of FNR by an uncharacterized mechanism. We report the results of microarray analysis, bioinformatic analysis, and chromatin immunoprecipitation, which revealed that ...[more]
